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Ecdysterone also known as ECDY, 20 Hydroxyecdysone or 20 E is a non-hormonal, plant or arthropod derived ingredient that is structurally like androgens. In plants it is commonly derived from the Cyanotis vaga, Ajuga turkestanica and Rhaponticum carthamoides species. As a supplement ecdysterone is suspected to have been used by Russian strength athletes (a "Russian Secret") as far back as the 1980's. Numerous studies have been conducted on ecdysterone with varying results. The most recent comprehensive study though was commissioned by the World Anti-Doping Agency (WADA) in 2019 with a scientific group that included the Department for Molecular & Cellular Sports Medicine at the German Sport University Cologne (1). These results were overall positive in the support of 20 Hydroxyecdysone. Further recent studies also seem to support positive findings. Ecdysterone supplements included in this category include ecdysone, ecdysterone, turkesterone and 20-hydroxyecdysone.
(1) Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, et al. (July 2019). "Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans". Archives of Toxicology. 93 (7): 1807–1816.