Hover/Touch To Zoom

Supplements Since 2004 Supplements Since 2004

TRUSTED STORE SINCE 2004 Free Fast Shipping $150+

Brick-And-Mortar Store Locations Across Australia Australian Store Locations

Alpha Lipoic Acid (ALA): Comprehensive Insights

Quick Summary

  • Alpha Lipoic Acid (ALA) is a powerful antioxidant found in the human body and certain foods, instrumental in energy production at the cellular level.
  • It is unique due to its dual solubility in both water and fat, allowing it to function effectively in various parts of the body's cells.
  • Natural sources of ALA include red meat, organ meats, and some vegetables, though supplements offer more concentrated forms.
  • ALA's health benefits extend to improving insulin sensitivity, aiding diabetic neuropathy, and potentially mitigating cardiovascular complications.
  • In terms of weight management, ALA boosts metabolic activity, aiding in fat processing and weight loss when combined with proper diet & exercise.
  • Generally safe for consumption, ALA can cause minor side effects for some; specific populations should seek medical advice before supplementation.
  • Dosage & timing of ALA intake depend on individual goals and health needs, with higher doses often used for therapeutic purposes.
  • Choosing ALA supplements requires attention to product quality, with a preference to use trusted products or brands.
  • ALA presents a promising addition to health regimes, offering various benefits, but it must be approached with informed caution & understanding.


In an era where dietary supplements have surged in popularity for their extensive health benefits, Alpha Lipoic Acid (ALA) emerges as a compound of significant interest. This article aims to delve deep into the intricacies of ALA, offering insights into its nature, potential benefits, safety considerations, & guidance on its optimal usage.

What is Alpha Lipoic Acid?

Alpha Lipoic Acid is an organic compound known for its antioxidant properties. Present in every cell of the human body, ALA is critical in converting glucose into energy during cellular respiration. Unlike other antioxidants, which are either water- or fat-soluble, ALA is both, allowing it to work in various parts of the body's cells.

Where Does Alpha Lipoic Acid Come From?

Naturally, ALA is found in minute quantities in several foods like red meat, organ meats (liver, heart), & yeast, particularly brewer's yeast. Additionally, various vegetables such as spinach, broccoli, & tomatoes contain this vital acid.

In the supplement industry, synthetic versions of ALA are produced to ensure high concentrations that offer therapeutic benefits.

Alpha Lipoic Acid Benefits

The health benefits of ALA are multifaceted, ranging from its potent antioxidant function, neutralizing harmful free radicals, to its role in energy metabolism. Scientific studies have highlighted ALA's contribution to managing conditions such as diabetes by improving insulin sensitivity, protecting against diabetic nerve damage, & reducing complications associated with cardiovascular diseases.

Furthermore, its antioxidant properties suggest a role in cancer prevention, though more research is needed in this area.

Alpha Lipoic Acid Benefits for Weight & Fat Loss

In the realm of weight management, ALA has shown promise in enhancing metabolic activity, suggestive of its potential in aiding weight loss & combating obesity. By influencing how the body processes fats & carbohydrates, ALA assists in moderating body weight.

Notably, combining ALA supplementation with a healthy diet & regular exercise has been observed to contribute to significant weight loss.

Alpha Lipoic Acid Safety & Side Effects

Generally recognized as safe when taken as recommended, ALA has a commendable safety profile. However, some individuals might experience minor side effects, including allergic reactions, skin rashes, or gastrointestinal disturbances.

Specific populations, such as pregnant women & those on medications (especially for diabetes & thyroid diseases), should consult healthcare professionals before initiating supplementation.

Alpha Lipoic Acid Recommended Doses & Ingredient Timing

Effective dosages of ALA vary depending on individual health goals. For general antioxidant support, smaller doses may be sufficient. In contrast, managing conditions such as diabetic neuropathy might require higher dosages.

Consuming supplements with meals can enhance the absorption of ALA, though specific timing recommendations can vary based on the targeted outcome & supplement formulation.

Alpha Lipoic Acid Supplements

The market offers a plethora of ALA supplements, with variations in strength & formulation. Consumers should opt for supplements that are manufactured by respected established brands such as Underground Labs ALA.

It's also wise for individuals to scrutinise product labels, seek guidance from industry professionals, & consider their health status before commencing supplementation.


Alpha Lipoic Acid stands out as a versatile & potent health-enhancing compound. Its benefits span from potent antioxidant properties to roles in weight management & disease mitigation. While ALA supplements offer a convenient way to obtain therapeutic doses, responsible use is paramount, emphasizing the necessity for informed decisions based on professional healthcare advice.

As the journey to optimal health continues, it becomes clear that compounds like ALA can be significant allies, provided they are approached with caution & understanding.

Burke et al (2003). Effect of alpha-lipoic acid combined with creatine monohydrate on human skeletal muscle creatine and phosphagen concentration. Int J Sport Nutr Exerc Metab, 13: 294-302
Cooke & Cribb (2008), Effective Nutritional Supplement Combinations IN Nutritional Supplements in Sports and Exercise. Ed Greenwood et al. Humana Press
Cremer et al (2006), Safety evaluation of α-lipoic acid (ALA). Regulatory Toxicology and Pharmacology, 46: 29-41
Estrada et al (1996), Stimulation of glucose uptake by the natural coenzyme α-lipoic acid/thioctic acid. Diabetes, 45: 1798-1804
Kim et al (2004), Effect of alpha-lipoic acid combined with creatine monohydrate on human skeletal muscle creatine and phosphagen concentration. Nature Medicine, 10: 727 - 733
Prietro-Hontoria et al (2009), Lipoic acid prevents body weight gain induced by a high fat diet in rats: Effects on intestinal sugar transport. Journal of Physiology and Biochemistry, 65: 43-40Ziegler et al (1995), Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant α-lipoic acid. Diabetologia, 38: 1425-1433

Contact Us
↑   Back To Top   ↑