What is Drostanolone (Masteron)?
Drostanolone is a steroid with both anabolic and androgenic properties. It is similar in structure to the male sex hormone Testosterone, and has similar effects. Drostanolone is commercially sold under the name Masteron.
Why use Drostanolone (Masteron)?
Drostanolone is prescribed by doctors in the treatment of a number of conditions. Like many other anabolic steroids, it can encourage the growth and proliferation of cells, and it is is used to treat conditions like anaemia (1). Drostanolone has been used in the past to treat certain types of breast cancer because it prevents the production of oestrogen, which encourages some types of cancer to grow. This usage has now been generally discontinued in favour of drugs with fewer side effects, due to the potential of the drug to induce male characteristics in women undergoing treatment (2).
Drostanolone is sometimes abused by athletes and bodybuilders to build muscle, and to retain strength and muscle definition during weight loss.
Drostanolone (Masteron) Side Effects
Like other anabolic steroids, when Drostanolone is abused for a non-therapeutic purpose in the absence of strict medical supervision, the potential for serious side effects is extremely high. These side effects can be irreversable, dangerous, and even fatal.
The psychological symptoms of steroid abuse are well known, and 'roid rage' is particularly prevalent amongst users of testosterone derivatives like Drostanolone. Withdrawal symptoms are also common amongst steroid users, and many studies have shown that steroid use is highly addictive, physically and psychologically (3).
Hormonal side effects go hand in hand with anabolic steroid abuse. Introducing testosterone analogues into the body turns off the body's own testosterone production within the Leydig cells in the testes. This is quite often irreversable, and the effects of low testosterone, including impotence, balding, hair loss, testicular atrophy, and female fat distribution, can be permanent. Drostanolone is also notorious for causing severe cystic acne (3). Drostanolone blocks oestrogen, so it has the opposite effect on women, who develop male characteristics, such as excess body hair, voice deepening, breast shrinkage and clitoral enlargement (2). Research has shown that drostanolone causes severe damage not only to the testes, but to the adrenal gland, which can lead to symptoms like tiredness, weakness, weight loss, goitre, and chronic heart and kidney disease (4).
Heart disease is an extremely serious side effect of steroid abuse, and it is very common due to the large number of different ways in which anabolic steroids damage the cardiovascular system. The risk of stroke and myocardial infarction is greatly increased through both the increase in cholesterol and atherosclerotic plaques, and the blood thickening that Drostanolone can cause (5). Steroid abuse causes increased blood presssure, which can cause aneurysm and damage to the blood vessels, and cause damage to the organs, particularly the liver and kidneys. Steroids cause damaging changes in the cardiac muscles. Enlargement of the walls of the heart can lead to reduced blood flow and heart failure (6).
Steroids like Drostanolone are generally bought and sold on the black market, where there is no guarantee of purity, efficacy or even safety. A recent study estimated that as many as one third of drugs on the market are fake, and these can be very difficult to distinguish from the real deal (7). The best case scenario with fake drugs is that you have wasted your money. Contamination is common in steroids, which are often produced in backyard labs with no quality control. Unexpected side effects, and severe reactions can be caused by unknown ingredients in the drug, while bacterial contamination can mean an abscess, septicemia, or gangrene (3).
Alternatives to Drostanolone (Masteron)
Many bodybuilders and athletes use natural supplements to support lean mass gains safely and effectively. Testosterone boosters increase the body's own production of this anabolic hormone in a healthy, sustainable way. Some of the best ingredients to look out for are:
Tribulus terrestris: This hugely popular plant extract contains a steroid analogue called protodioscin that packs on muscle and enhances strength and focus without any of the side effects. Tribulus has been used by men all over the world to boost their size and virility. Elemental Nutrition Massive Muscle Fuel 2.0 is one of the most potent sources of protodioscin out there.
D-Aspartic Acid: is a naturally occurring amino acid that has shown some phenomenal results in boosting testosterone levels.
Aromatase Inhibitors: Aromatase is the enzyme responsible for converting testosterone to oestrogen. These products are made for people looking for something to maximise testosterone and minimise side effects. BPI's A-HD is packed with safe, natural ingredients that get results.
(1) Pizzuto J, Conte G, Sinco A, Morales M, Avilés A, Ambríz R, Fernández A. Use of androgens in acquired aplastic anaemia. Relation of response to aetiology and severity. Acta Haematol. 1980;64(1):18-24.
(2) Chowdhury MS, Banks AJ, Bond WH, Jones WG, Ward HW. A comparison of drostanolone propionate (Masteril) and nandrolone decanoate (Deca-durabolin) in the treatment of breast carcinoma. Clin Oncol 1976;2 (3): 203–6.
(3) Hartgens F, Kuipers H. Effects of androgenic-anabolic steroids in athletes. Sports Med. 2004;34(8):513-54.
(4) Takahashi M, Tatsugi Y, Kohno T. Endocrinological and pathological effects of anabolic-androgenic steroid in male rats. Endocr J. 2004 Aug;51(4):425-3
(5) Güneş Y, Erbaş C, Okuyan E, Babalik E, Gürmen T. Myocardial infarction with intracoronary thrombus induced by anabolic steroids. Anadolu Kardiyol Derg. 2004 Dec;4(4):357-8.
(6) (9) Lane HA, Grace F, Smith JC, Morris K, Cockcroft J, Scanlon MF, Davies JS. Impaired vasoreactivity in bodybuilders using androgenic anabolic steroids. Eur J Clin Invest. 2006 Jul;36(7):483-8.
(7) Da Justa Neves DB, Marcheti RG, Caldas ED. Incidence of anabolic steroid counterfeiting in Brazil. Forensic Sci Int 2013; 228(1-3): e81-3