Since Cellucor’s founding in 2002, it has become a company known for a top quality and extremely favourable product range, not to mention their aesthetically superior packaging. Within a decade, Cellucor has stamped its name on the supplement industry as a force to be reckoned with when it comes to innovation and results.
Cellucor’s weight loss range of products is plentiful and encompassing of all different areas of weight loss. Here we look at Cellucor’s fat metaboliser - the Cellucor WS1.
What Is It?
Cellucor’s WS1 is Cellucor’s fat metabolising product from their weight loss range. WS1 is said to help with the regulation of blood sugars and insulin spikes which can result in fat storage as well as containing well known fat metabolising ingredients to synergistically help with fat loss.
Cellucor’s WS1 is an interesting mix of ingredients, the concept of which is somewhat inspired with ingredients aimed at metabolising already stored fats as well as ingredients aimed at decreasing fat storage in general.
While many know about the commonly used fat burning ingredient L-carnitine, it’s cousin; acetyl-L-carnitine is becoming increasingly used in a wide variety of supplements including fat loss and pre-workout products. With strong antioxidant properties and neuroprotective qualities (brain protection), acetyl-L-carnitine can also help with insulin response1 and body composition2. That is, it has been shown to help regulate blood sugars by making us more sensitive to insulin. Less insulin released means less fat storage as insulin is an extremely anabolic hormone. Acetyl-L-carnitine has also been shown to improve fat metabolism (oxidation).
Coenzyme Q10 is also included in Cellucor’s WS1. An important compound involved in energy production, its inclusion in a fat metabolising product is a rather ingenious idea. As fat is an excellent source of fuel and energy, reductions in fat storage and a increase in fat metabolism can result in a decrease in energy levels and exercise capacity. By increasing levels of coenzyme Q10, Cellucor WS1 can help negate any energy reduction effects by improving energy production processes and recovery capacity while reducing fatigue3. Furthermore, a recent study4 was able to show a combination of l-carnitine and coenzyme Q10 was able to decrease levels of lipoprotein(a), a fat transporter which at high levels is a risk for heart disease.
Garlic, a well known immunity booster is also among the mix of ingredients in Cellucor’s WS1. While garlic has had strong supportive studies of it as an anti-inflammatory and anti-cancer ingredient, it is only recently that garlic has been used as a potential ingredient to help with diabetes and obesity. While research is still being conducted on the exact mechanisms, garlic has been shown to improve insulin sensitivity14 as well as improving body composition13 and cholesterol parameters15. Animal studies have also shown it to be helpful in the management of obesity12.
Difference From the Competition
Cellucor’s WS1 contains a notable different ingredient from many other fat metabolising products; pTeroPure™, a proprietary formulation with high amounts of the compound pterostilbene. Pterostilbene is a compound commonly found in blueberries and dark skinned grapes, which has similar properties to resveratrol, the beneficial compound found in red grapes, other fruits and red wine. While research on pterostilbene is still light, studies have shown it to be promising in cancers as well as diabetes, due to its ability to reduce blood sugar levels5. Animal studies on high blueberry diets have also shown it to be beneficial in reducing blood fats and cholesterol levels6,7,.
Of Particular Interest
The use of bitter melon extract in Cellucor WS1’s blend is an excellent move with a recent flood of positive scientific studies on the power of bitter melon, also known as bitter gourd on such issues as malaria, viral diseases such as chickenpox and herpes to cancers and heart disease risk. Still other studies have been able to show beneficial effects of bitter melon and its extracts for the control of blood sugar levels8 as well as fat metabolism9,10,11. While further human studies are needed to make any conclusive statements about bitter melon and its extracts, there is high hope that it is a powerful new ingredient with a wide range of beneficial effects.
The Black Sheep
Including the two fat soluble vitamins A and E in the mixture is an excellent idea for a fat metabolising product as a reduction in fat intake or increased fat metabolism could put you at risk of deficiency of those vitamins. However, one has to wonder why Cellucor didn’t include the other two equally important fat soluble vitamins D and K.
Who It's For
Cellucor’s WS1 is an inspired and original fat metabolising supplement suitable for anyone looking to lose some body fat and/or improving their regulation of blood sugars and insulin release. Remember to make sure you’re getting plenty of vitamins A, D, E and K if you are considering taking Cellucor’s WS1.
Stacking Cellucor WS1
Cellucor WS1, while being a great standalone product can also be stacked with other fat loss products in Cellucor’s range including Cellucor P6, D4, L2 and T7.
_1. Mingorance C, Rodríguez-Rodríguez R, Justo ML, Alvarez de Sotomayor M, Herrera MD. ‘Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders.’ Vasc Health Risk Manag. 2011;7:169-76. Epub 2011 Mar 28.
2. Benedini S, Perseghin G, Terruzzi I, Scifo P, Invernizzi PL, Del Maschio A, Lazzarin A, Luzi L. ‘Effect of L-acetylcarnitine on body composition in HIV-related lipodystrophy.’ Horm Metab Res. 2009 Nov;41(11):840-5. Epub 2009 Jul 13.
3. See article on Coenzyme Q10
4. Shojaei M, Djalali M, Khatami M, Siassi F, Eshraghian M. ‘Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy.’ Iran J Kidney Dis. 2011 Mar;5(2):114-8.
5. Pari L, Satheesh MA. ‘Effect of pterostilbene on hepatic key enzymes of glucose metabolism in streptozotocin- and nicotinamide-induced diabetic rats.’ Life Sci. 2006 Jul 10;79(7):641-5. Epub 2006 Apr 17.
6. Kalt W, Foote K, Fillmore SA, Lyon M, Van Lunen TA, McRae KB. ‘Effect of blueberry feeding on plasma lipids in pigs.’ Br J Nutr. 2008 Jul;100(1):70-8. Epub 2007 Dec 17.
7. Kim H, Bartley GE, Rimando AM, Yokoyama W. ‘Hepatic gene expression related to lower plasma cholesterol in hamsters fed high-fat diets supplemented with blueberry peels and peel extract.’ J Agric Food Chem. 2010 Apr 14;58(7):3984-91.
8. Leung L, Birtwhistle R, Kotecha J, Hannah S, Cuthbertson S. ‘Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review.’ Br J Nutr. 2009 Dec;102(12):1703-8.
9. Senanayake GV, Fukuda N, Nshizono S, Wang YM, Nagao K, Yanagita T, Iwamoto M, Ohta H. ‘Mechanisms Underlying Decreased Hepatic Triacylglycerol and Cholesterol by Dietary Bitter Melon Extract in the Rat.’ Lipids. 2012 Mar 29. [Epub ahead of print]
10. Jayasooriya AP, Sakono M, Yukizaki C, Kawano M, Yamamoto K, Fukuda N. ‘Effects of Momordica charantia powder on serum glucose levels and various lipid parameters in rats fed with cholesterol-free and cholesterol-enriched diets.’ J Ethnopharmacol. 2000 Sep;72(1-2):331-6.
11. Nerurkar PV, Lee YK, Nerurkar VR. ‘Momordica charantia (bitter melon) inhibits primary human adipocyte differentiation by modulating adipogenic genes.’ BMC Complement Altern Med. 2010 Jun 29;10:34.
12. Ban JO, Lee DH, Kim EJ, Kang JW, Kim MS, Cho MC, Jeong HS, Kim JW, Yang Y, Hong JT, Yoon DY. ‘Antiobesity Effects of a Sulfur Compound Thiacremonone Mediated via Down-regulation of Serum Triglyceride and Glucose Levels and Lipid Accumulation in the Liver of db/db Mice.’ Phytother Res. 2012 Jan 6. doi: 10.1002/ptr.3729. [Epub ahead of print]
13. Lee MS, Kim IH, Kim CT, Kim Y. ‘Reduction of body weight by dietary garlic is associated with an increase in uncoupling protein mRNA expression and activation of AMP-activated protein kinase in diet-induced obese mice.’ J Nutr. 2011 Nov;141(11):1947-53. Epub 2011 Sep 14.
14. Padiya R, Khatua TN, Bagul PK, Kuncha M, Banerjee SK. ‘Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats.’ Nutr Metab (Lond). 2011 Jul 27;8:53.
15. Reinhart KM, Talati R, White CM, Coleman CI. ‘The impact of garlic on lipid parameters: a systematic review and meta-analysis.’ Nutr Res Rev. 2009 Jun;22(1):39-48.